Journal of Pediatric Perspectives

original article

Stimulation of Child Growth and Development and Nutritional Status Among Children Aged 24-59 Months: A Cross-Sectional in Indonesia

Fadira Nurifa Fawaida; Tantut Susanto; Fahruddin Kurdi; Wahyuni Fauziah

Volume 13, Issue 7 , July 2025, Pages 19540-19551

https://doi.org/10.22038/jpp.2025.89981.5575

Abstract

Background: Stunting remains a significant global nutritional issue, with Indonesia’s prevalence at 21.5% in 2023, and Jember Regency in East Java recording a high prevalence ... Read More

original article

Pain Management Strategies for Children with Blood Diseases and Cancer During Venipuncture and IV Line Insertion: A Descriptive-Analytical Study on Nurses

Sara Jahangiri; Mohammad Reza Mosaddegh; Mahdi Jahangiri; Ali Ghasemi; Marziyeh Ghorbani; Mojgan Bahari

Volume 13, Issue 7 , July 2025, Pages 19552-19560

https://doi.org/10.22038/jpp.2025.88812.5564

Abstract

Background: Children with blood diseases are frequently subjected to invasive treatments such as venipuncture and IV line insertion (V-IVLI). Pain from V-IVLI harms children. Nurses' ... Read More

original article

Diabetic Ketoacidosis Before, During, and After The COVID-19 Pandemic

Nosrat Ghaemi; Kosar Alidadi; Sepideh Bagheri; Nafiseh Pourbadakhshan; Majid Khadem-Rezaiyan

Volume 13, Issue 7 , July 2025, Pages 19561-19569

https://doi.org/10.22038/jpp.2025.90034.5579

Abstract

Background: Diabetic ketoacidosis (DKA) can be the initial sign of type 1 diabetes in children upon diagnosis. Some studies have examined the impact of the coronavirus disease 2019 ... Read More

review article

Precision Medicine in Neonatal Intensive Care: Tailoring Therapies for Preterm Infants

Rakesh Kotha

Volume 13, Issue 7 , July 2025, Pages 19570-19578

https://doi.org/10.22038/jpp.2025.89733.5569

Abstract

Background: Preterm birth, which affects 10% of global births, increases the risks of respiratory distress syndrome (RDS) and sepsis. The varied treatment responses necessitate personalized ... Read More Background: Preterm birth, which affects 10% of global births, increases the risks of respiratory distress syndrome (RDS) and sepsis. The varied treatment responses necessitate personalized therapies. Precision medicine, utilizing genomic and metabolomic data, offers tailored interventions to enhance outcomes in neonatal intensive care units (NICUs).Objective: The Objective is to evaluate genomic and metabolomic advancements for customizing treatments for RDS and sepsis in preterm infants, highlighting applications, limitations, and future prospects.Methods: A narrative review synthesized literature from 2015 to 2024 on genomic profiling, pharmacogenomics, and metabolomics in neonatal care. The literature was sourced from PubMed, Scopus, and DOAJ. Studies were included if they focused on preterm infants (<37 weeks’ gestation) with RDS or sepsis, evaluated genomic or metabolomic interventions, and reported clinical outcomes. Priority was given to studies with clear methodologies, including prospective or retrospective designs, and those addressing diverse populations (e.g., geographic or ethnic variability) where possible. The validation status of biomarkers was noted to assess clinical applicability. Exclusion criteria included studies lacking a neonatal focus or peer-reviewed publication. Data were qualitatively synthesized to highlight applications, limitations, and future prospects.Results: Genomic profiling identifies SFTPB variants, guiding surfactant therapy for RDS with 20–30% dosing variability. Pharmacogenomics optimizes sepsis antibiotic regimens, with CYP2C19 variants reducing vancomycin toxicity by 15%. Metabolomic biomarkers, like phosphatidylcholines and lactate, enable early diagnosis of RDS and sepsis with 85–90% sensitivity. Challenges include data complexity, ethical issues, and limited access in low-resource settings.Conclusion: Personalized medicine improves neonatal care through individualized therapies but requires validation, cost reduction, and ethical frameworks for equitable implementation.

case report

Septic Shock Following Chickenpox in Pediatrics: A Case Report and Review of Literature

Majid Sezavar; Shahabaddin Sorouri; Gholamreza Khademi; Yasaman Fatemeh Khazaee; Maryam Naseri

Volume 13, Issue 7 , July 2025, Pages 19579-19586

https://doi.org/10.22038/jpp.2025.88717.5562

Abstract

Background: Chickenpox is a viral disease that is benign and self-limiting, known for its skin rash appearance. Musculoskeletal complications, such as septic arthritis and osteomyelitis, ... Read More

case report

Anaphylaxis with The Manifestation of Convulsions

Aikaterini Salavoura; Nikoleta Lalioti; Panagiota Sotiropoulou; Dimitrios Chatzis

Volume 13, Issue 7 , July 2025, Pages 19587-19592

https://doi.org/10.22038/jpp.2025.87964.5546

Abstract

Febrile episodes accompanied by convulsions are a common pediatric condition. We present the clinical history and laboratory evaluation of a 2.5-year-old boy with a concomitant food ... Read More

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Volume & Issue: Volume 13, Issue 7, July 2025, Pages 19540-19592

Stimulation of Child Growth and Development and Nutritional Status Among Children Aged 24-59 Months: A Cross-Sectional in Indonesia

Abstract

Pain Management Strategies for Children with Blood Diseases and Cancer During Venipuncture and IV Line Insertion: A Descriptive-Analytical Study on Nurses

Abstract

Diabetic Ketoacidosis Before, During, and After The COVID-19 Pandemic

Abstract

Precision Medicine in Neonatal Intensive Care: Tailoring Therapies for Preterm Infants

Abstract

Septic Shock Following Chickenpox in Pediatrics: A Case Report and Review of Literature

Abstract

Anaphylaxis with The Manifestation of Convulsions

Abstract