Journal of Pediatric Perspectives

Journal of Pediatric Perspectives

Association between Transient Tachypnea of the Newborn and Serum Vitamin D Levels in Infants and Mothers in Natural Childbirth

Document Type : original article

Authors
Sareh Farshadfar 1
Fatemeh Hosseini 2
Ghazal Kahrizi 3
Arezoo Haseli 4
Azam Brimavandi 4
1 Department of Pediatrics, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
2 School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
3 Medical Student, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran.
4 Clinical Research Development Center, Motazedi Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
10.22038/jpp.2024.82497.5481
Abstract
Background: Transient Tachypnea of the Newborn (TTN) is one of the most common causes of respiratory distress, shortly after birth, and is generally a benign, self-limited condition. Meanwhile, a lot of studies have linked vitamin D (VitD) levels with probably contributing to neonatal lung development.
Methods: This study aimed to assess whether the serum levels of VitD are associated with TTN in infants and mothers in natural childbirth. This descriptive-analytical research was performed on 39 infants with TTN and their mothers and 39 control infants and their mothers referred to Motazedi hospital in Kermanshah University of Medical Sciences. Serum concentrations of VitD were measured in the first 12-24 h of postnatal age in both infants and mothers.
Results: In the present study, no significant difference was found between healthy and TTN groups in terms of gender, mother's education level, drug use, asthma, diabetes, 1th min Apgar score, mother's age, birth weight, and birth height. But, there was a significant difference between the two groups of control and intervention in terms of 5th min Apgar score, and birth order. The mean levels of serum VitD were significantly lower in both TTN neonate patients and mothers. The results of the Pearson correlation coefficient indicated that there is a significant relationship between serum VitD levels of mothers and term infants in both groups.
Conclusion: We observed that maternal VitD levels can be preventive for the development of TTN in infants through improving respiratory distress, and potentially shortening the duration of tachypnoea in natural childbirth.
Keywords
Natural childbirth
Respiratory distress
Term newborns
Transient tachypnea of the newborn
Vitamin D
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Journal of Pediatric Perspectives
Volume 12, Issue 9
September 2024
Pages 18988-18994