Journal of Pediatric Perspectives

The Effect of Oral Vitamin A in the Prevention of Retinopathy of Prematurity in Premature Infants with Low Birth Weight

Maryam Mohammadi; Maryam Shokouhi Solgi; Nasrin Jiriaee; Mohmammad Amin Rezaei; Behnaz Basiri

Volume 12, Issue 7 , July 2024, , Pages 18902-18911

https://doi.org/10.22038/ijp.2024.82758.5484

Abstract

Background: Retinopathy of Prematurity (ROP) is one of the most common complications in premature babies, whose severe disease can have a long-term effect on the visual performance ... Read More Background: Retinopathy of Prematurity (ROP) is one of the most common complications in premature babies, whose severe disease can have a long-term effect on the visual performance of babies. In some studies, it has been shown that the administration of vitamin A may be effective in these infants; however, sufficient studies have not been conducted in this field. This randomized clinical trial aimed at investigating the effect of oral vitamin A in the prevention of ROP among premature infants with low birth weight, admitted to the neonatal intensive care unit of Fatemiyeh Hospital.Methods: In this clinical trial, 66 premature babies with a gestational age of less than 34 weeks who were admitted to the neonatal intensive care unit due to prematurity and respiratory distress were included. The patients were randomly divided into two groups and one group received 3000 units of oral vitamin A daily for 28 days or until discharge, in addition to the usual daily care. In the control group, only usual care was given. Stages of ROP were evaluated according to the International Classification of Retinopathy of Prematurity (ICROP). The rates of Necrotizing Entero-Colitis (NEC), Broncho-Pulmonary Dysplasia (BPD) and Intraventricular Hemorrhage (IVH) were investigated in both groups.Results: Both groups had no statistically significant differences in terms of basic variables. No side effects were observed in the intervention group. The rates of Necrotizing Entero-Colitis (NEC), Broncho-Pulmonary Dysplasia (BPD) and Intraventricular Hemorrhage (IVH) were lower in the intervention group, but did not show a statistically significant difference with the control group. The incidence rate of ROP was found to be 43.4% in the intervention group and 59.4% in the control group (P=0.172). Among the 14 infants of the intervention group, where retinopathy of prematurity occurred, 7 patients had grades II and III, while 17 cases (89.5%) of the 19 affected infants had grades II and III in the control group (P=0.019).Conclusion: Our findings revealed that the administration of oral vitamin A in premature infants with low weight can be an effective therapeutic strategy to reduce the risk of retinopathy.

Is Maternal Hypertension a Reducing Factor for Intraventricular Hemorrhage in Iranian Preterm Newborns?

Mandana Kashaki; Maryam Saboute; Maryam Esmaeili Allafi; Elahe Norouzi

Volume 10, Issue 8 , August 2022, , Pages 16469-16476

https://doi.org/10.22038/ijp.2022.63523.4840

Abstract

Background: Hypertensive disorders of pregnancy including preeclampsia can be associated with preterm birth and infant mortality and morbidity. It seems that intraventricular hemorrhage ... Read More

Risk Factors for Neonatal Mortality at St Camille Hospital in Ouagadougou, Burkina Faso

Paul Ouedraogo; Nicaise Zagre; Théodora Mahoukèdè Zohoncon; Abdoul Ouattara; Viviane Bissyande; Solange Ouedraogo/Yugbare; Jacques Simpore

Volume 8, Issue 2 , February 2020, , Pages 10817-10825

https://doi.org/10.22038/ijp.2020.44524.3687

Abstract

Background: Neonatal mortality remains a public health concern in developing countries such as Burkina Faso. Improving the survival rate of newborns requires a good knowledge of the ... Read More

Common Factors Associated With Child Deaths, at a Tertiary Care Centre in Irbid Government, Jordan

Shereen Hamadneh; Manal Kassab; Sawsan Abu-hammad; Nahla Al-bayyari; Jehan Hamadneh; Nail Obeidat; Liqaa Raffee; Rola Saqan

Volume 6, Issue 8 , August 2018, , Pages 8021-8030

https://doi.org/10.22038/ijp.2018.31212.2757

Abstract

Background: Understanding causes of death among children is crucial to decrease mortality rate. Identifying specific causes of under-five mortality help in developing possible prioritize ... Read More

Study of Causes of Neonatal Mortality and its Related Factors in the Neonatal Intensive Care Unit of Imam Reza Hospital in Kermanshah, Iran during (2014-2016)

Homa Babaei; Mohana Dehghan; Leila Mohammadi pirkashani

Volume 6, Issue 5 , May 2018, , Pages 7641-7649

https://doi.org/10.22038/ijp.2017.28212.2441

Abstract

Background Neonatal mortality rate is one of the main indicators of health care systems in each country. The first step in improving the level of these indicators is to identify the ... Read More

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Keywords = Prematurity

The Effect of Oral Vitamin A in the Prevention of Retinopathy of Prematurity in Premature Infants with Low Birth Weight

Abstract

Is Maternal Hypertension a Reducing Factor for Intraventricular Hemorrhage in Iranian Preterm Newborns?

Abstract

Risk Factors for Neonatal Mortality at St Camille Hospital in Ouagadougou, Burkina Faso

Abstract

Common Factors Associated With Child Deaths, at a Tertiary Care Centre in Irbid Government, Jordan

Abstract

Study of Causes of Neonatal Mortality and its Related Factors in the Neonatal Intensive Care Unit of Imam Reza Hospital in Kermanshah, Iran during (2014-2016)

Abstract