Document Type : original article
Authors
1 Behavioral disease research center, Kermanshah University of Medical Sciences, Kermanshah, Iran.
2 Neonatal Department, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
3 Department of Social Medicine, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
4 Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran
Abstract
Introduction: Retinopathy of prematurity (ROP) is one of the most common complications in premature babies, whose severe disease can have a long-term effect on the visual performance of babies. In some studies, it has been shown that the administration of vitamin A may be effective in these infants, however, sufficient studies have not been conducted in this field. This randomized clinical trial aimed at investigating the effect of oral vitamin A in the prevention of ROP in premature infants with low birth weight, admitted to the neonatal intensive care unit of Fatemiyeh Hospital.
Materials and methods: In this clinical trial, 66 premature babies with a gestational age of less than 34 weeks who were admitted to the neonatal intensive care unit due to prematurity and respiratory distress were included in the study. The patients were randomly divided into two groups and one group received 3000 units of oral vitamin A daily for 28 days or until discharge, in addition to the usual daily care. In the control group, only usual care was given. Stages of ROP were evaluated according to the International Classification of Retinopathy of Prematurity (ICROP). The rates of necrotizing enterocolitis (NEC), bronchopulmonary dysplasia (BPD) and intraventricular hemorrhage (IVH) were investigated in both groups.
Keywords
)