Journal of Pediatric Perspectives

Journal of Pediatric Perspectives

Peutz-Jeghers Syndrome in a 7-Year-Old Male Presenting with Jejunojejunal Intussusception and a Giant Incidental Meckel’s Diverticulum: A Case Report

Document Type : case report

Authors
Ali Samady Khanghah 1
Mostafa Abrishami 2
Hamidreza Kianifar 3
Farzaneh Afshari 4
Khashayar Atqiaee 2
1 Department of Surgery, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran.
2 Department of Pediatric Surgery, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
3 Department of Pediatric Gastroenterology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Department of Pathology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
10.22038/jpp.2026.94847.5632
Abstract
Background: Peutz-Jeghers syndrome (PJS) is an autosomal dominant disorder characterized by gastrointestinal hamartomatous polyposis, most commonly the small intestine. Although intussusception is a recognaized complication of PJS, primary intussusception is uncommon in children older than three years of age, necessitating a high index of suspicion for underlying pathological lead points.
Case Presentation: We report a case of type B1 PJS in a seven-year-old male who initially presented with an acute abdomen. Subsequent laparotomy revealed a jejunojejunal intussusception along with an incidentally discovered large Meckel’s diverticulum. Notably, the patient lacked the classic mucocutaneous hyperpigmentation typically associated with PJS.
Conclusion: Approaching an acute abdomen in a pediatric patient requires a careful diagnostic evaluation. In children older than three years presenting with intussusception, secondary causes such as PJS must be considered, even in the absence of pathognomonic mucocutaneous pigmentation.
Keywords
Intussusception
Meckel Diverticulum
Peutz-Jeghers Syndrome
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Journal of Pediatric Perspectives
Volume 14, Issue 3
March 2026
Pages 20019-20027