Evaluation of Electrocardiographic Parameters in Diabetes Mellitus Type I in Children and Adolescent

Noori, Noor Mohammad; Teimouri, Alireza; Nakhaee Moghadam, Maryam; Kasravi, Maryam

doi:10.22038/ijp.2019.40337.3417

Evaluation of Electrocardiographic Parameters in Diabetes Mellitus Type I in Children and Adolescent

Authors

Noor Mohammad Noori ¹

Alireza Teimouri ¹

Maryam Nakhaee Moghadam ¹

Maryam Kasravi ²

¹ Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.

² School of Medicine, Zahedan University of Medical Sciences and Health Services, Zahedan, IR Iran.

10.22038/ijp.2019.40337.3417

Abstract

Background

Cardiovascular complications are continuing to be a major cause of morbidity and mortality in diabetes mellitus type I (DMTI). The study aimed to evaluate the rate of changes in ECG parameters in children with DMTI compared with healthy children.

Materials and Methods

This case-control study was performed on 140 participants which consisted of 70 patients with DMTI (case group) matched in sex and age with 70 healthy ones (control group) in two centers in collaboration with Ali Asghar Hospital, Zahedan, Iran, between March 2017 and April 2018. Electrocardiography was performed in all participants (patients and healthy), and heart rate, QT (start of the Q wave and the end of the T wave) QTc interval (QT/√ RR), QTd (dispersion between maximum and minimum of QT), and QTcd (dispersion between maximum and minimum of QTc) were measured. Duration of diabetic and level of HbA1c were obtained for patients and the effects of these parameters on ECGs were investigated.

Results

Height, weight and heart rate were higher in the patients (P<0.001) when S in V₁ was higher in case (6.16±3.23) compared to the control group (4.33± 2.22) (P<0.001). QT (356.71±27.28 compared to 347.00±23.55), QTd (49.00±14.66 compared to 41.21±8.32), and QTcd (60.47±17.32 compared to 49.93±10.44) were higher in case group (p<0.05). Hemoglobin A1C (p=0.043) was higher in boys and heart rate was higher in girls (p<0.001). Diabetic time duration and HbA_1c normality states did not change the length of these parameters in diabetic patients.

Conclusion

Based on the results, QT, QTd, QTc and QTcd were higher in patients with DMTI. Diabetic time duration and HbA1c states did not change the ECG parameters in diabetic patients.

Keywords

Adolescents

Children

Diabetes mellitus

QT changes