Prevalence of Diabetic Neuropathy in Patients with Type 1 Diabetes in Iran: A Systematic Review and Meta-Analysis

Document Type : systematic review

Authors

1 Assistant Professor of Neurology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran

2 Assistant Professor of Internal Medicine, Department of Internal Medicine, School of Medicine, Shahid Mostafa Khomaeini Hospital, Ilam University of Medical sciences, Ilam, Iran

3 Assistant Professor of Pulmonary Diseases, Department of Internal Medicine, School of Medicine, Shahid Mostafa Khomaeini Hospital, Ilam University of Medical sciences, Ilam, Iran.

Abstract

Background: Diabetic Neuropathy (DN) is one of the prevalent complications of Type 1 Diabetes (T1D), which reduces the patient's ability to maintain his/her balance by reducing proprioception.
Methods: In this meta-analysis, conducted by the use of PARISMA and SMART checklists, articles published on the prevalence of DN in T1D patients in Iran were included in the study. The search was carried out by two specialists in internal medicine who were well versed in the subject of search and meta-analysis articles; and the validity of the search was confirmed by a third person who had a specialist degree in pulmonary (internal medicine). After entering references into Endnote 8 software and removing duplicate articles, data extraction was performed and analysis was done using CMA3 software.
Result: The prevalence of DN in 10 reviewed articles was 33.3% (confidence interval (CI) =23.5-44.7), and in 3 articles, mild and moderate DN status was reported, and the prevalence of mild DN was 32.6% (confidence interval (CI) = 19.1-49.7) and the average DN was equal to 6.8% (confidence interval (CI) = 2.6-16.5). Also, the prevalence of DN in people over 15 years old was reported as 30.9% (confidence interval (CI) = 15.9-51.5) and in people under 15 years old was 43.1% (confidence interval (CI) = 28.5-59.1).
Conclusion: It is suggested that further meta-analysis studies be conducted on the other complications of diabetes in these patients.

Keywords

References

  1. Ayele K, Tesfa B, Abebe L, Tilahun T, Girma E: Self-care behavior among patients with diabetes in Harari, Eastern Ethiopia: the health belief model perspective. PloS one 2012, 7(4):e35515.
  2. Ali A, Khan A, Butt Ar: Prevalence of Risk Factors of Diabetic Nephropathy and Their Association with Estimated Gfr in Patients of Type 2 Diabetes Mellitus. Gomal Journal of Medical Sciences 2023, 21(1):31-36.
  3. Najim MK, Lahhob QR, Abbas HJ, Alidrisi HA, Ibrahim ZJ, Budaiwi ZK, Abdul-Jabbar ZH, Kadham MJ, Maatook MA: Association of serum apelin and atherogenic indices in patients with primary thyroid diseases. Eurasian Chemical Communications 2023, 5(7):588-597.
  4. Tol A, Sharifirad G, Eslami AA, Alhani F, Tehrani MM, Shojaeezadeh D: Factors influencing self-management behavior in type-2 diabetes patients: a strategy proposed to be adopted when planning theory/model based interventions. Journal of School of Public Health & Institute of Public Health Research 2012, 9(4):21-32.
  5. Tayebi Myaneh Z, Rashvand F, Abdolahi F: Relationship between sleep quality and self-management in type II diabetes patients. Hayat 2020, 26(3):238-250.
  6. Rajaa Taher H, Habib Saifalla P: Study of the level of signal-regulated kinase 5 (ERK5) in patients with coronary heart disease with and without diabetes mellitus type 2. Eurasian Chemical Communications 2023, 5(5):425-440.
  7. Azizi M, Arsalani N, Mohammadi Shahboulaghi F, Hosseinzadeh S, Rajab A: The effect of self-care education on the control of diabetes complications, medications and HbA1C in adolescents with type 1 diabetes. Hayat 2017, 22(4):350-361.
  8. Khalid Hussein M, Habib Saifalla P: Estimation of insulin resistance and creatine kinase among Iraqi patients with type 2 diabetes mellitus. Eurasian Chemical Communications 2022, 4(12):1193-1200.
  9. Abbas Al-Ameri M, M. Al-Rubaei Z: Vascular endothelial growth factor –A (VEGF-A) and its receptor (VEGFR-2) in rheumatoid arthritis patients with type 2 diabetes mellitus. Eurasian Chemical Communications 2022, 4(12):1201-1208.
  10. Kazeminezhad B, Taghinejad H, Borji M, Tarjoman A: The effect of self-care on glycated hemoglobin and fasting blood sugar levels on adolescents with diabetes. Journal of Comprehensive Pediatrics 2018, 9(2).
  11. Mazlominezhad A, Moghadam FA: Evaluation of quality of life and self-efficacy in adolescents with amblyopia. Journal of Medicine and Life 2022, 15(4):499-503.
  12. Solati H, Sahebalzamani M, Adhami Moghadam F: Effect of Family-Based Care Training by Tele-nursing on Emotional Reactions in Mothers of Children with Bone Marrow Transplantation. Journal of Mazandaran University of Medical Sciences 2021, 30(192):156-161.
  13. Göthesson J, Håkansson L, Olinder AL, Hanberger L, Mörelius E, Nilsson S, Forsner M: Children's and adolescent's narratives about pain and negative experiences in diabetes treatment. Journal for Specialists in Pediatric Nursing 2023, 28(1):e12396.
  14. d'Annunzio G, Accogli A, Tallone R, Bolloli S, Lorini R: Environmental factors and type 1 diabetes mellitus in the pediatric age group. In: Genes and Autoimmunity-Intracellular Signaling and Microbiome Contribution. edn.: IntechOpen; 2013.
  15. Akram M, Riaz T, Elbossaty WF, Zafar S, Munir N, Saeed MM: Microorganisms in the Pathogenesis and Management of Type 1 Diabetes (T1D). Role of Microorganisms in Pathogenesis and Management of Autoimmune Diseases: Volume II: Kidney, Central Nervous System, Eye, Blood, Blood Vessels & Bowel 2023:427-439.
  16. Borrego N, Bommakanti M, Radack J, Hamilton L, Wilson D: Polyglandular Autoimmunity: Two Cases of Type 1 diabetes (T1D) accompanied by Addison’s disease (AD). 2023.
  17. Borji M, Tarjoman A, Seymohammadi R, Salimi E, Otaghi M: Effects of continuous care model on blood pressure in patients with type ii diabetes. Journal of Clinical and Diagnostic Research 2018, 12(4):JC7-JC10.
  18. James S, Perry L, Lowe J, Harris M, Colman PG, Craig ME: Blood pressure in adolescents and young adults with type 1 diabetes: data from the Australasian Diabetes Data Network registry. Acta Diabetologica 2023:1-7.
  19. Karimian M, Gholami A, Farzaei MH, Stefanucci A, Mollica A, Mahmoudi Y, Shahrabady S, Tarjoman A, Borji M: The effect of angipars™ on wound healing in patients with diabetes: A systematic review. Journal of Chemical Health Risks 2020, 10(3):195-202.
  20. Kleef DG, Hussein KR, Abbas HJ: Evaluation of procollagen 1 N propeptide for predicting osteomyelitis and epithelial neutrophil activator-78 for early wound healing in patients with diabetic foot. Eurasian Chemical Communications 2023, 5(5):441-449.
  21. Malone JI, Gao X, Lorenzi GM, Raskin P, White NH, Hainsworth DP, Das A, Tamborlane W, Wallia A, Aiello LP: Retinopathy during the first 5 years of type 1 diabetes and subsequent risk of advanced retinopathy. Diabetes care 2023, 46(4):680-686.
  22. Rasmussen VF, Thrysøe M, Karlsson P, Vestergaard ET, Kristensen K, Christensen A-MR, Nyengaard JR, Terkelsen AJ, Brock C, Krogh K: Early Gastrointestinal Neuropathy Assessed by Wireless Motility Capsules in Adolescents with Type 1 Diabetes. Journal of Clinical Medicine 2023, 12(5):1925.
  23. Jung J, Kim M-G, Kang Y-J, Min K, Han K-A, Choi H: Vibration perception threshold and related factors for balance assessment in patients with type 2 diabetes mellitus. International Journal of Environmental Research and Public Health 2021, 18(11):6046.

24. Turcot K, Allet L, Golay A, Hoffmeyer P, Armand S: Investigation of standing balance in diabetic patients with and 

without peripheral neuropathy using accelerometers. Clinical Biomechanics 2009, 24(9):716-721.

  1. Manafi H, Aminianfar A: Effect of whole body vibration on ankle joint proprioception and balance in patients with diabetic neuropathy. Koomesh 2022, 24(3):347-357.
  2. Miri F, Gholami F, MOKABERIAN M: Effect of resistance training on general health, happiness and its correlation with glycemic control in diabetic men with peripheral neuropathy. 2021.
  3. Abdulmlik S, Saifullah PH, A. Al-a’adhami M: Evaluation of vitamin B12 and methylmalonic acid levels as markers with neuropathy in patients of type 2 diabetes mellitus. Eurasian Chemical Communications 2022, 4(10):956-965.
  4. Hatefi M, Komlakh K, Nouri L: Investigating the effect of methylprednisolone pulse on the treatment of back pain. Romanian Journal of Military Medicine 2022, 125(2):264-268.
  5. Karbasfrushan A, Karimiyarandi H: Role of vitamin D on knee osteoarthritis pain: a systematic review. Eurasian Chemical Communications 2022, 4(12):1241-1250.
  6. Hatefi M, KomLakh K: Investigation of the effect of Duloxetine on pain status of patients with spinal cord injuries: a systematic review of drug therapy. Eurasian Chemical Communications 2022, 4(3):256-262.
  7. Karimiyarandi H, Karbasfrushan A: EFFECT OF DULOXETINE ON PAIN RELIEF IN PATIENTS UNDERGOING ARTHROPLASTY SURGERY: A SYSTEMATIC REVIEW. Gomal Journal of Medical Sciences 2022, 20(4):213-220.
  8. Toopchizadeh V, Shiva S, Khiabani N-Y, Ghergherechi R: Electrophysiologic pattern and prevalence of subclinical peripheral neuropathy in children and adolescents with type I diabetes mellitus in Iran. Saudi medical journal 2016, 37(3):299.
  9. Ghaemi N, Hasanabadi H, Ashrafzadeh F, Sarvari S, Rahimi H, Hashemian S: Peripheral neuropathy in children and adolescents with insulin-dependent diabetes mellitus. Iranian Journal of Child Neurology 2018, 12(2):83.
  10. Vasigh A, Abdi A, Borji M, Tarjoman A: The prevalence of neuropathy among type 1 diabetic adolescents in Iran: a systematic review and meta-analysis. International journal of adolescent medicine and health 2019, 33(4):20180223.
  11. Sarshar N, Chamanzari H: The Survey of Complications in Thepatients of Gonabad Diabetic Clinic. 2003.
  12. Hasani N, Khosrawi S, Hashemipour M, Haghighatiyan M, Javdan Z, Taheri MH, Kelishadi R, Amini M, Barekatein R: Prevalence and related risk-factors of peripheral neuropathy in children with insulin-dependent diabetes mellitus. Journal of research in medical sciences: the official journal of Isfahan University of Medical Sciences 2013, 18(2):132.
  13. Omrani GHR, Soveid M, Rajaii H, Sadegholvaad Aa: The Incidence of Chronic Diabetic Complications During a 12 Years Period in Patients Referring To Clinics of Shiraz University Of Medical Sciences. Journal of Diabetes and Metabolic Disorders 2004, 3:68.
  14. Kiani J, Moghimbeigi A, Azizkhani H, Kosarifard S: The prevalence and associated risk factors of peripheral diabetic neuropathy in Hamedan, Iran. Archives of Iranian medicine 2013, 16(1):0-0.
  15. olfatifar M, Karami M, Hosseini SM, shokri P: Prevalence of Chronic Complications and Related Risk Factors of Diabetes in Patients Referred to the Diabetes Center of Hamedan Province. Avicenna Journal of Nursing and Midwifery Care 2017, 25(2):69-74.
  16. Abbasian M, Delvarianzadeh M: Dietary intake of micronutrients in first-degree healthy, diabetic and IGT relatives of type II diabetic patients. Journal of knowledge & health 2008, 2(4):17-21.
  17. Khorasani E: Prevalence of peripheral neuropathy and its related factors in diabetic children, Neishabour city, Iran. International Journal of Pediatrics 2018, 6(12):8707-8714.
  18. Karamifar H, Mooadab M, Karamizadeh Z, Amirhakimi G: Evaluation of peripheral neuropathy in patients with type 1 diabetes mellitus by bedside scoring procedure. 2007.
  19. Daryabari SH, Asadollah A, Moghadam FA, Dorostkar R, Bahramifar A, Aghamollaei H: Detection of COVID-19 in tears of ICU-admitted patients with SARS-CoV-2 infection. International Ophthalmology 2022, 42(3):723-727.
  20. Shokri M, Karimian M, Mansouri F, Mahdikhani S, Borji M, Solaimanizadeh L, Tarjoman A, Soltany B, Gholami A: Laboratory and radiologic findings in pediatrics with COVID-19: A systematic review. Archives of Clinical Infectious Diseases 2020, 15(3).
  21. Yovera-Aldana M, Velásquez-Rimachi V, Huerta-Rosario A, More-Yupanqui M, Osores-Flores M, Espinoza R, Gil-Olivares F, Quispe-Nolazco C, Quea-Vélez F, Morán-Mariños C: Prevalence and incidence of diabetic peripheral neuropathy in Latin America and the Caribbean: A systematic review and meta-analysis. PloS one 2021, 16(5):e0251642.
  22. Sahin SY, Kilit TP, Kocak FE: Effect of Methimazole on Serum Concentrations of Oxidative Stress Markers in Patients with Hyperthyroidism in the Population of Kutahya City, Turkey. Gomal Journal of Medical Sciences 2022, 20(3).
  23. Abdel-Motal UM, Abdelalim EM, Abou-Saleh H, Zayed H: Neuropathy of type 1 diabetes in the Arab world: a systematic review and meta-analysis. Diabetes research and clinical practice 2017, 127:172-180.
  24. D’Souza RS, Barman R, Joseph A, Abd-Elsayed A: Evidence-based treatment of painful diabetic neuropathy: a systematic review. Current Pain and Headache Reports 2022, 26(8):583-594.
  25. Sobhani S, Asayesh H, Sharifi F, Djalalinia S, Baradaran HR, Arzaghi SM, Mansourian M, Rezapoor A, Ansari H, Masoud MP: Prevalence of diabetic peripheral neuropathy in Iran: a systematic review and meta-analysis. Journal of Diabetes & Metabolic Disorders 2014, 13:1-7.
  26. BONDAR AC, POPA AR: Diabetic neuropathy prevalence and its associated risk factors in two representative groups of type 1 and type 2 diabetes mellitus patients from Bihor County. Maedica 2018, 13(3):229.
  27.  
Journal of Pediatric Perspectives
Volume 11, Issue 6
June 2023
Pages 17935-17946

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