Hepatoblastoma Related Tumor Thrombosis Extended to IVC, Ra and Pulmonary Artery Branches: A Case Report

Document Type : case report

Authors

1 Department of Pediatrics, Faculty of Medicine, Islamic Azad University of Medical, Mashhad, Iran.

2 Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

3 Pediatric Nephrologist, Assistant professor ,Department of Pediatric, Division of Nephrology Mashhad University of Medical Sciences, Dr Sheikh Hospital ,Mashhad Iran.

4 Obstetrician and gynecologist, Department of obstetrics gynecology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5 Department of Pediatric, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Mashhad, Iran

Abstract

Hepatoblastoma (HB) is a rare malignant tumor of the liver; but is the most common malignancy of liver in infancy and childhood that usually occurs in the first three years of life. These tumors are usually present by abdominal mass, abdominal pain, anemia, thrombocytosis, and high serum levels of AFP; and may cause decreased appetite and weight loss.
Complications such as ascites, GIB, icterus, splenomegaly and vascular thrombosis may occur, while hepatic vein or inferior vena cava thrombosis is quite rare especially with a spread to right atrium and pulmonary artery branches. Multidisciplinary therapy by a pediatric oncologist, a pathologist, an experienced radiologist, a pediatric cardiologist and a pediatric surgeon is very important to diagnose and manage the condition. We report on the case of an infant with a huge abdominal mass and much extended tumor thrombosis till the pulmonary artery branches that shrunk appropriately after the first course of chemotherapy.

Keywords

References

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Journal of Pediatric Perspectives
Volume 11, Issue 2
February 2023
Pages 17448-17452

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