The maternal and neonatal outcomes of pregnant women with definite COVID-19

Document Type : original article

Authors

1 Maternal, Fetal and Neonatal Research Center, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran

2 Department of Perinatology, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran

3 Department of Anesthesiology, School of Medicine, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran

4 Department of Perinatology, Yas Hospital, Tehran University of Medical Sciences, Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Science, Tehran, Iran.

5 Faculty of Educational and Psychology, Department Of Psychology, University Of Sistan and Baluchestan, Sistan and Baluchestan, Iran

6 Obstetrics and Gynecology Department, Pregnancy Health Research Center, Ali IbneAbitaleb Hospital, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran

7 Microbiology student of Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract

Background: This study aimed to assess the symptoms and clinical laboratory data of pregnant women with COVID-19 in their second or third trimester of pregnancy as well as their maternal and neonatal outcomes.
Methods: This retrospective observational study was conducted on 177 pregnant women with COVID-19 who were admitted to Yas hospital (affiliated with Tehran University of Medical Sciences), and Ali-ibn-Abi-Talib hospital (affiliated with Zahedan University of Medical Sciences).
Results: There was significant higher complaints including fever (p-value=0.015), cough (p-value=0.028), fatigue (p-value=0.002), dyspnea (p-value=0.022), and lower hemoglobin level (p-value=0.009) in patients who were in their third trimester compared to those who were in their second trimester. 9.6% (n=17) of the patients had severe disease and needed ICU admission. There was a significant variation regarding gestational age (p-value=0.022) in pregnant women admitted to ICU compared to the other ones. During the study, delivery happened in 108 (61%) pregnant women. Fetal distress following meconium deification (p-value=0.041), need to MGSO4 (p-value=0.001), IUFD (p-value=0.006), need for blood transfusion (p-value=0.004), and neonatal death (p-value<0.001) were significantly higher in patients who needed ICU admission.
Conclusion: Higher gestational weeks are the main risk factor for severe COVID-19 disease. Although vertical transmission is rare; due to the higher risk of perinatal outcomes, the delivery should be done in a center with a NICU department.

Keywords

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Journal of Pediatric Perspectives
Volume 10, Issue 10
October 2022
Pages 16803-16810

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