Study of Vitamin D Level in Children with Non-specific Musculoskeletal Pain

Mahmoodzadeh, Hashem; Nasimfar, Amir; Sadeghi, Ebrahim; Macooie, Agayar; Gazavi, Ahad; Rasouli, Javad; Fakour, Sanam; Noroozi, Mehran; Gheibi, Shahsanam; Rezazadeh, Amin; Nikibakhsh, Ahmad

doi:10.22038/ijp.2016.20988.1756

Study of Vitamin D Level in Children with Non-specific Musculoskeletal Pain

Authors

Hashem Mahmoodzadeh ¹

Amir Nasimfar ²

Ebrahim Sadeghi ²

Agayar Macooie ²

Ahad Gazavi ²

Javad Rasouli ³

Sanam Fakour ⁴

Mehran Noroozi ²

Shahsanam Gheibi ⁵

Amin Rezazadeh ⁶

Ahmad Nikibakhsh ¹

¹ Department of Pediatric Nephrology, Urmia University of Medical Sciences, Urmia, Iran.

² Urmia University of Medical Sciences, Urmia, Iran.

³ Department of Epidemiology and Biostatistic, School of Medical Sciences, Urmia University of Medical Sciences, Urmia, Iran.

⁴ Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.

⁵ Maternal and Childhood Obesity Research Center, Urmia University of Medical Sciences, Urmia, Iran.

⁶ IAU, School of Veterinary Medicine, Urmia branch, Urmia, Iran.

10.22038/ijp.2016.20988.1756

Abstract

Background
Vitamin D deficiency is known as a one of the underlying causes of Idiopathic musculoskeletal pain (IMSP). This study aimed to evaluate the correlation between serum vitamin D (Cholecalciferol) status in patient with Non-specific Musculoskeletal Pain and healthy children.
Materials and Methods
Seventy-seven children (aged 3–14 years), with IMSP were included as cases and 90 healthy subjects were selected for control group. Demographic characteristics and biochemical levels of vitamin D and Parathyroid hormone (PTH), were obtained. Data were analysis using SPSS version 17.0 software.
Results
Results showed that vitamin D means levels of patients and healthy children were significantly different (19.5 + 8.84 ng/mL versus 12.7 + 11.89 ng/mL), respectively (P<0.05). Also, there was a significant difference between PTH level in both healthy and patient subjects (P<0.001). Mean levels of vitamin D in both groups were below the normal range, but lower in control group (P<0.001).
Conclusion
Deficiency of vitamin D was suggested as the probable identified risk factors for IMSP in children. The results of our study did not reveal clear correlation between vitamin D deficiencies in children which suffer IMSP compared the healthy children.

Keywords

Children

IMSP

Iran

Pain

Vitamin D