Document Type : review article
Authors
Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract
Auto-inflammatory diseases (AIDs) are a diverse group of disorders characterized by inappropriate activation of the innate immune system, leading to chronic inflammation. In children, these conditions can significantly impact multiple organs, including the kidneys. This review article is based on the most recent studies published after 2020, focusing on various autoimmune diseases and their impact on kidney function. This review aims to provide a comprehensive overview of auto-inflammatory diseases and their renal involvement in pediatric patients, focusing on advancements in understanding the molecular mechanisms, diagnostic strategies, and treatment options. By examining the latest research, this article aims to enhance clinical awareness of renal manifestations and improve management strategies for pediatric rheumatologists.
Keywords
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