Document Type : original article
Authors
1 Student Research Committee , Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
2 Department of Nephrology, Hormozgan University of Medical Sciences, Bandar-Abbas, Iran
Abstract
Background
Vomiting and nausea are common symptoms of Gastroenteritis (GE) in children, and high statistics in emergency department visits. Vitamin B6, which plays a significant role in preventing vomiting in pregnant women, is one of the options for controlling GE. This study examines the effect of pyridoxine (vitamin B6) in children with GE.
Method
The study population of this research was a case-control including all children aged 6 months to 12 years with mild to moderate dehydration who were admitted to the children's hospital in Bandar Abbas city during 2021-2022. The study groups included two control and intervention groups. The treatment group consisted of patients aged 6 months to 14 years of both genders who received pyridoxine to control nausea and vomiting based on weight.
Results
A total of 70 individuals were included in our study, of whom 48.57% were female and 51.43% were male. The percentage of dehydration in patients with gastroenteritis in the control group was 64.6±1.59%, and in the group treated with vitamin B6, it was 32.6±1.46%, with no significant correlation between the percentage of dehydration in the control and vitamin B6-treated groups. No significant correlation between the amount of fluid received in the control and vitamin B6-treated groups and the mean length of hospital stay in the control group was, with no significant correlation between the length of hospital stay in the control and vitamin B6-treated groups.
Conclusion
Pyridoxine drug was not effective in treating vomiting caused by acute gastroenteritis in children compared to the control sample. Although vitamin B6 is effective in controlling inflammation, it was not able to reduce GE complications.
Keywords