Sinus Histiocytosis in a Child: A Rare Case Report

Ramakrishnan, Lavanya; Taksande, Amir; Meshram, Revat

doi:10.22038/ijp.2024.67369.5029

Sinus Histiocytosis in a Child: A Rare Case Report

Document Type : case report

Authors

Lavanya Ramakrishnan ¹

Amir Taksande ²

Revat Meshram ³

¹ Department of Paediatrics, Jawaharlal Nehru Medical College, Sawangi Meghe, Wardha, Maharashtra, India.

² Professor and Head of Department, Dept. of Pediatrics, Jnmc, Sawangi Meghe, Wardha, India.

³ MD, Associate Professor, Department of Pediatrics, Jawaharlal Nehru Medical College, Sawangi, Wardha, India.

10.22038/ijp.2024.67369.5029

Abstract

Background: Rosai-Dorfman disease is a self-limiting condition caused by histiocyte proliferation within the sinusoids of lymph nodes and in the extranodal tissue. It is a rare disease, particularly in children, that progresses with extensive lymphadenopathy.
Case Presentation: We report the case of a 5-year-old child who presented with an enlarged cervical lymph node. Fine Needle Aspiration Cytology (FNAC) was done, which was suggestive of ‘active lymphoid hyperplasia with sinus histiocytosis’
Conclusion: In this case, after careful analysis of the biopsied specimen, a conservative approach was adopted. The patient was discharged and advised for follow-up. On follow-up, after 2 weeks the size of the lymph node had decreased.

Keywords

Cervical Lymphadenopathy

Non-Langerhans Cells

Rosai-Dorfman Disease

Sinus Histiocytosis

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