Journal of Pediatric Perspectives

Journal of Pediatric Perspectives

Prevalence of Diabetic Nephropathy in Patients with Type 1 Diabetes in Iran: A Systematic Review and Meta-Analysis

Document Type : systematic review

Authors
Behzad Darabi 1
Maryam Alemzadeh 2
Saba Sardari 3
1 Department of Pediatrics, School of Medicine Emam Khomeini Hospital, Ilam University of Medical sciences, Ilam, Iran
2 Assistant Professor of Pediatric Intensive Care, Department of Pediatrics, School of Medicine Mofid Children's Hospital, Shahid Beheshti, University of Medical Sciences, Tehran, Iran
3 Msc of Neonatal Intensive Care Nursing, Lorestan University of Medical Sciences, Khorramabad, Iran, sabasardar2018@yahoo.com
10.22038/ijp.2023.70827.5206
Abstract
Background: Diabetic nephropathy (DN) is one of the complications of diabetes. The present study was conducted with the aim of determining the prevalence of DN in patients with D1T in Iran.
Methods: This meta-analysis and systematic review included the articles published from 2000 to 2022, in domestic (Iran) and international journals. Search keywords included diabetes, type 1 diabetes, D1T, nephropathy, Iran, children, and adolescents, which were searched in Persian and English. The search was conducted by two members of the research team independently and the outcomes were finally approved by the third person who was considered as the manager of the research team. The extracted data was analyzed by CMA3 software.
Results: The overall prevalence of DN was found to be 10% (confidence interval (CI) = 3.4-26.1). The lowest and highest prevalences of DN were found to be reported as 0.04% and 30.8%, respectively.
Conclusion: Considering the high prevalence of DN in patients with T1DM, it is suggested that the necessary preventive measures be taken to reduce the complications of diabetes in these patients
Keywords
Keywords: diabetic nephropathy
type 1 diabetes
Iran
  1. Mazlominezhad A, Moghadam FA: Evaluation of quality of life and self-efficacy in adolescents with amblyopia. Journal of Medicine and Life 2022, 15(4):499-503.
  2. Solati H, Sahebalzamani M, Adhami Moghadam F: Effect of Family-Based Care Training by Tele-nursing on Emotional Reactions in Mothers of Children with Bone Marrow Transplantation. Journal of Mazandaran University of Medical Sciences 2021, 30(192):156-161.
  3. Borji M, Tarjoman A, Seymohammadi R, Salimi E, Otaghi M: Effects of continuous care model on blood pressure in patients with type ii diabetes. Journal of Clinical and Diagnostic Research 2018, 12(4):JC7-JC10.
  4. Pandey A, Chawla S, Guchhait P: Type‐2 diabetes: Current understanding and future perspectives. IUBMB life 2015, 67(7):506-513.
  5. Pirdeghan A, Shafieyan AM, Esna-Ashari F, Borzouei S: Evaluation Medication-Related Beliefs and Treatment in Patients with Diabetes Typ2 in Hamadan in 2021. Iranian Journal of Diabetes and Lipid Disorders 2022, 22(5):312-320.
  6. Kazeminezhad B, Taghinejad H, Borji M, Tarjoman A: The Effect of Self-Care on Glycated Hemoglobin and Fasting Blood Sugar Levels on Adolescents with Diabetes. 2018, 9(2):e62661.
  7. Gholami A, Hemati R, Khorshidi A, Borji M, Kafashian M, Kalvandi G, Tarjoman A, Mahdikhani S, Shokri M: The Prevalence of Clinical Symptoms in Children and Adolescents with Covid-19: A Systematic Review and Meta-Analysis Study. International Journal of Pediatrics 2020, 8(10):12177-12188.
  8. Shokri M, Tarjoman A, Borji M, Solaimanizadeh L: Investigating psychological problems in caregivers of pediatrics with cancer: A systematic review. Journal of Child and Adolescent Psychiatric Nursing 2020, 33(4):229-238.
  9. Howard SG: Exposure to environmental chemicals and type 1 diabetes: an update. J Epidemiol Community Health 2019, 73(6):483-488.
  10. Mokhtari E, Sarshin A, Feizolahi F, Alijani E: The Effect of Resistance Training and Endothelial Stem Cell Injection on Βeta-Actin, Phosphorylated and Total AKT of Skeletal Muscle in Type 1 Diabetic Rats. Iranian Journal of Diabetes and Lipid Disorders 2022, 22(2):69-80.
  11. Lim L-M, Chang J-M, Kuo H-T: Diabetic Kidney Disease in Post-Transplant Diabetes Mellitus: Causes, Treatment and Outcomes. Biomedicines 2023, 11(2):470.
  12. Huang JX, Casper TC, Pitts C, Myers S, Loomba L, Ramesh J, Kuppermann N, Glaser N: Association of acute kidney injury during diabetic ketoacidosis with risk of microalbuminuria in children with type 1 diabetes. JAMA pediatrics 2022, 176(2):169-175.
  13. Garey CJ, Clements MA, McAuliffe‐Fogarty AH, Obrynba KS, Weinstock RS, Majidi S, Ross CS, Rioles NA: The association between depression symptom endorsement and glycemic outcomes in adolescents with type 1 diabetes. Pediatric diabetes 2022, 23(2):248-257.
  14. Smith-Palmer J, Bae JP, Boye KS, Norrbacka K, Hunt B, Valentine WJ: Evaluating health-related quality of life in type 1 diabetes: a systematic literature review of utilities for adults with type 1 diabetes. ClinicoEconomics and outcomes research 2016:559-571.
  15. Xu Q, Wang L, Sansgiry SS: A systematic literature review of predicting diabetic retinopathy, nephropathy and neuropathy in patients with type 1 diabetes using machine learning. J Med Artif Intell 2020, 3(6).
  16. Vasigh A, Abdi A, Borji M, Tarjoman A: The prevalence of neuropathy among type 1 diabetic adolescents in Iran: a systematic review and meta-analysis. International journal of adolescent medicine and health 2021, 33(4).
  17. Ataee R, Esmaeeli H: The Renoprotective Effects of Sodium Valproate as a Histone Deacetylase Inhibitor on Diabetic Nephropathy. Journal of Babol University of Medical Sciences 2017, 19(9):45-53.
  18. Lim AK: Diabetic nephropathy–complications and treatment. International journal of nephrology and renovascular disease 2014:361-381.
  19. Zhang J, Liu J, Qin X: Advances in early biomarkers of diabetic nephropathy. Revista da Associação Médica Brasileira 2018, 64:85-92.
  20. Cohen-Bucay A, Viswanathan G: Urinary markers of glomerular injury in diabetic nephropathy. International journal of nephrology 2012, 2012.
  21. Seyed Ahmadi S, Periodic A, Svensson A-M, Wedel H, Rathsman B, Nyström T, Ludvigsson J, Lind M: Risk factors for nephropathy in persons with type 1 diabetes: a population-based study. Acta Diabetologico 2022, 59(6):761-772.
  22. Boswell L, Ventura-Aguiar P, Alejaldre A, Navarro-Otano J, Cofan F, Serés-Noriega T, Pané A, Montagud-Marrahi E, Molina-Andújar A, Ruiz M: Diabetic neuropathy is independently associated with worse graft outcomes and incident cardiovascular disease after pancreas transplantation: A retrospective cohort study in Type 1 diabetes. Transplantation 2023, 107(2):475-484.
  23. Hashemi H, Rezvan F, Pakzad R, Ansaripour A, Heydarian S, Yekta A, Ostadimoghaddam H, Pakbin M, Khabazkhoob M: Global and Regional Prevalence of Diabetic Retinopathy; A Comprehensive Systematic Review and Meta-analysis. Semin Ophthalmol 2022, 37(3):291-306.
  24. Mostofizadeh N, Rashidi A, Hashemi-Dehkordi E, Hashemipour M, Attari A, Mehrkesh M, Madihi Y: The Frequency of Diabetic Nephropathy in Children and Adolescents with Type 1 Diabetes Mellitus. Journal of Isfahan Medical School 2019, 37(529):617-623.
  25. Arad B, Chegini V, Talati N, Homaei A, Saffari F: High Frequency of Nephropathy among the Iranian Children and Adolescents with Type 1 Diabetes. Journal of Inflammatory Diseases 2021, 25(2):85-92.
  26. olfatifar M, Karami M, Hosseini SM, shokri P: Prevalence of Chronic Complications and Related Risk Factors of Diabetes in Patients Referred to the Diabetes Center of Hamedan Province. Avicenna Journal of Nursing and Midwifery Care 2017, 25(2):69-74.
  27. Abbasian M, Delvarianzadeh M: Dietary intake of micronutrients in first-degree healthy, diabetic and IGT relatives of type II diabetic patients. Journal of knowledge & health 2008, 2(4):17-21.
  28. Sarshar N, H: C: The survey of complications in the patients of Gonabad Diabetes Clinic. Ofogh-e Danesh. J Gonabad Uni Med Sci Health Services 2003:62-69.
  29. Jadawji C, Crasto W, Gillies C, Kar D, Davies MJ, Khunti K, Seidu S: Prevalence and progression of diabetic nephropathy in South Asian, white European and African Caribbean people with type 2 diabetes: A systematic review and meta‐analysis. Diabetes, Obesity and Metabolism 2019, 21(3):658-673.
  30. Rosolowsky ET, Skupien J, Smiles AM, Niewczas M, Roshan B, Stanton R, Eckfeldt JH, Warram JH, Krolewski AS: Risk for ESRD in type 1 diabetes remains high despite renoprotection. Journal of the American society of nephrology 2011, 22(3):545-553.
  31. Zhang X-X, Kong J, Yun K: Prevalence of diabetic nephropathy among patients with type 2 diabetes mellitus in China: a meta-analysis of observational studies. Journal of diabetes research 2020, 2020.
  32. Wagnew F, Eshetie S, Kibret GD, Zegeye A, Dessie G, Mulugeta H, Alemu A: Diabetic nephropathy and hypertension in diabetes patients of sub-Saharan countries: a systematic review and meta-analysis. BMC Research Notes 2018, 11(1):565.
  33. Piccoli GB, Clari R, Ghiotto S, Castelluccia N, Colombi N, Mauro G, Tavassoli E, Melluzza C, Cabiddu G, Gernone G: Type 1 diabetes, diabetic nephropathy, and pregnancy: a systematic review and meta-study. The Review of Diabetic Studies: RDS 2013, 10(1):6.
  34. Raile K, Galler A, Hofer S, Herbst A, Dunstheimer D, Busch P, Holl RW: Diabetic nephropathy in 27,805 children, adolescents, and adults with type 1 diabetes: effect of diabetes duration, A1C, hypertension, dyslipidemia, diabetes onset, and sex. Diabetes care 2007, 30(10):2523-2528.
  35. Andersen AR, Christiansen JS, Andersen JK, Kreiner S, Deckert T: Diabetic nephropathy in type 1 (insulin-dependent) diabetes: An epidemiological study. Diabetologia 1983, 25(6):496-501.
Journal of Pediatric Perspectives
Volume 11, Issue 7
July 2023
Pages 18080-18088