Document Type : original article
Authors
1 Associate Professor in Nursing, Mother and Child Care Research Center, School of Nursing and Midwifery, Hamadan University of Medical Sciences, Hamadan, Iran.
2 Department of Biochemistry, Hamedan Branch, Islamic Azad University, Hamedan, Iran
3 Deputy of Treatment, Hamadan University of Medical Sciences, Hamadan, Iran
4 Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
5 Nahavand School of Allied Medical Sciences, Hamadan University of Medical Sciences, Hamadan, Iran
Abstract
Background: The prevalence of Coronavirus and COVID-19 disease has had far-reaching effects in various aspects. Considering the importance of a comprehensive study of the disease of Covid-19 and its epidemic, this study was conducted.
Methods: This research evaluated COVID-19 in pregnant women and children under 13 years of age in Nahavand City, west of Iran, from March 2020 to March 2021. Information about the epidemiology of COVID-19 disease was extracted from the infectious diseases unit of Nahavand Health Center. Descriptive statistics, chi-square test, and Logistic regression model were used to evaluate the disease. All data of this study were analyzed using SPSS software, version 16. The inclusion condition in this study was having positive RT-PCR. No general vaccination was performed at the time of this study.
Results: 22.5% of the children had a positive RT-PCR test. The age group of 12-13 years had the most patients. 36.3% of children needed hospital treatment. Pregnant women comprised 2.08% of the infected population of Nahavand city in the defined time. 6.7% of them were hospitalized. The mean age of the pregnant women was 28.4 years. The mortality rate in both groups was zero.
Conclusion: COVID-19 disease, in pregnant women, was significantly correlated with age, contact with COVID-19, underlying disease and hospitalization. According to the analysis of variance, there was a significant correlation between the disease and age groups in children under 13 years old
Keywords
- Yang P, Wang X. COVID-19: a new challenge for human beings. Cellular & molecular immunology. 2020; 17(5):555-7.
- Melo P, Barbosa JM, Jardim L, Carrilho E, Portugal J. COVID-19 management in clinical dental care. Part I: epidemiology, public health implications, and risk assessment. International Dental Journal. 2021; 71(3):251-62.
- Weisberg SP, Connors TJ, Zhu Y, Baldwin MR, Lin W-H, Wontakal S, Szabo PA, Wells SB, Dogra P, Gray J, Idzikowski E, Stelitano D, Bovier FT, Davis-Porada J, Matsumoto R, Li Poon MM, Chait M, Mathieu C, Horvat B, Decimo D, Hudson KE, Zotti FD, Bitan ZC, Carpia FL, Ferrara SA, Mace E, Milner J, Moscona A, Hod E, Porotto M, Farber DL. Distinct antibody responses to SARS-CoV-2 in children and adults across the COVID-19 clinical spectrum. Nature immunology. 2021; 22(1):25-31.
- Kim SH, Choi Y, Lee D, Lee H, Kim JH, Choi ES, Jung YM, Lee J, Choe PG, Lee JY, Do Y, Park CW, Park JS, Jun JK, Lee SM, Lee JY. Impact of COVID-19 on pregnant women in South Korea: Focusing on prevalence, severity, and clinical outcomes. Journal of infection and public health. 2022 Jan 17: 270-276.
- Schmitt G, Labdouni S, Soulimani R, Delamare C, Bouayed J. Oxidative stress status and vitamin D levels of asymptomatic to mild symptomatic COVID‐19 infections during the third trimester of pregnancy: A retrospective study in Metz, France. Journal of Medical Virology. 2022 Jan 21: 2167–2173.
- Hyde Z. Difference in severe acute respiratory syndrome coronavirus 2 attack rate between children and adults may reflect bias. Clinical Infectious Diseases. 2022; 74(1):152-5.
- Zambrano LD, Ellington S, Strid P, Galang RR, Oduyebo T, Tong VT, Woodworth KR, Nahabedian III JF, Azziz-Baumgartner E, Gilboa SM, Meaney-Delman D. Update: characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status—United States, January 22–October 3, 2020. Morbidity and Mortality Weekly Report. 2020 Nov 6; 69(44):1641.
- Overton EE, Goffman D, Friedman AM. The epidemiology of COVID-19 in pregnancy. Clinical Obstetrics and Gynecology. 2022 Mar; 65(1):110.
- Chen L, Li Q, Zheng D, Jiang H, Wei Y, Zou L, Feng L, Xiong G, Sun G, Wang H, Zhao Y. Clinical characteristics of pregnant women with Covid-19 in Wuhan, China. New England Journal of Medicine. 2020 Jun 18; 382(25):e100.
- Shoji K, Tsuzuki S, Akiyama T, Matsunaga N, Asai Y, Suzuki S, Iwamoto N, Funaki T, Yamada M, Ozawa N, Yamaguchi K, Miyairi I, Ohmagari N. Clinical characteristics and outcomes of COVID-19 in pregnant women: a propensity score matched analysis of the data from the COVID-19 Registry Japan. Clinical Infectious Diseases. 2022 Jan 17; ciac 028.
- Liang H, Acharya G. Novel coronavirus disease (COVID-19) in pregnancy: What clinical recommendations to follow? 2020 Jul; 99(7):951.
- Ludvigsson JF. Systematic review of COVID‐19 in children shows milder cases and a better prognosis than adults. Acta paediatrica. 2020; 109(6):1088-95.
- Bhuiyan MU, Stiboy E, Hassan MZ, Chan M, Islam MS, Haider N, Jaffe A, Homaira N. Epidemiology of COVID-19 infection in young children under five years: A systematic review and meta-analysis. Vaccine. 2021; 39(4):667-77.
- Dooling K. The Advisory Committee on Immunization Practices’ updated interim recommendation for allocation of COVID-19 vaccine—United States, December 2020. MMWR Morbidity and mortality weekly report. 2021; 69.
- Donati S, Corsi E, Maraschini A, Salvatore MA, Group ICW, Arena MG, et al. SARS‐CoV‐2 infection among hospitalized pregnant women and impact of different viral strains on COVID‐19 severity in Italy: a national prospective population‐based cohort study. BJOG: An International Journal of Obstetrics & Gynaecology. 2022; 129(2):221-31.
- Jafari M, Pormohammad A, Sheikh Neshin SA, Ghorbani S, Bose D, Alimohammadi S, Basirjafari S, Mohammadi M, Rasmussen-Ivey C, Razizadeh MH, Nouri-Vaskeh M, Zarei M. Clinical characteristics and outcomes of pregnant women with COVID‐19 and comparison with control patients: A systematic review and meta‐analysis. Reviews in medical virology. 2021; 31(5):1-16.
- Villar J, Ariff S, Gunier RB, Thiruvengadam R, Rauch S, Kholin A, Roggero P, Prefumo F, Vale MSd, Cardona-Perez JA, Maiz N, Cetin I, Savasi V, Deruelle P, Easter SR, Sichitiu J, Conti CPS, Ernawati E, Mhatre M, Teji JS, Liu B, Capelli C, Oberto M, Salazar L, Gravett MG, Cavoretto PI, Nachinab VB, Galadanci H, Oros D, Ayede AI, Sentilhes L, Bako B, Savorani M, Cena H, García-May PK, Etuk S, Casale R, Abd-Elsalam S, Ikenoue S, Aminu MB, Vecciarelli C, Duro EA, Usman MA, John-Akinola Y, Nieto R, Ferrazi E, Bhutta ZA, Langer A, Kennedy SH, Papageorghiou AT. Maternal and neonatal morbidity and mortality among pregnant women with and without COVID-19 infection: the INTERCOVID multinational cohort study. JAMA pediatrics. 2021; 175(8):817-26.
- Qeadan F, Mensah NA, Tingey B, Stanford JB. The risk of clinical complications and death among pregnant women with COVID-19 in the Cerner COVID-19 cohort: a retrospective analysis. BMC pregnancy and childbirth. 2021 Dec; 21(1):1-4.
- Hantoushzadeh S, Shamshirsaz AA, Aleyasin A, Seferovic MD, Aski SK, Arian SE, Pooransari P, Ghotbizadeh F, Aalipour S, Soleimani Z, Naemi M. Maternal death due to COVID-19. American journal of obstetrics and gynecology. 2020 Jul 1; 223(1):109-e1.