Authors
- Saeedeh Talebi 1
- Seyed Javad Sayedi 2
- Golnaz Ranjbar 3
- Majid Khadem Rezaeian 4
- Hanie Bbarghchi 5
- golnaz Kazemi sefat 6
- Mohammad Safarian 7
- Hamidreza Kianifar 8
1 Department of Nutrition, Faculty of medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2 Assistant Prof of Pediatric Pulmonology, Mashhad University of Medical Sciences
3 Department of Nutrition, Faculty of medicine, Mashhad University of Medical sciences, Mashhad, Iran
4 clinical research development unit of Akbar hospital Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
5 Nutrition department, Faculty of medicine Mashhad University of Medical Sciences (MUMS), Mashhad, Iran
6 Department of Molecular Medicine, Faculty of Advanced Technology, Iran University of Medical Sciences
7 Department of Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran
8 Department of Gastroenterology,Faculty of medicine,Mashhad university of medical sciences,Mashhad,Iran
Abstract
Background: The present study aimed to translate the cystic fibrosis questionnaire-revised (CFQ-R) for children with cystic fibrosis (CF) into Persian and evaluate the reliability and validity of the instrument.
Methods: About eighty individuals including children and their parents were enrolled in this cross-sectional study. Demographic characteristic and disease severity parameters of the subjects were recorded. After translation of the CFQ-R to Persian, the participants completed the parent or child translated version of the CFQ-R, as well as the PedsQL 4.0. Reliability and validity analyses were, then, carried out.
Results: The forward-backward translation was employed in this study. The total content validity ratio (CVR) and content validity index (CVI) were above 0.8 and at least 0.49, respectively. The internal reliability of each domain was acceptable (Cronbach alpha coefficients 0.65-0.91). Appropriate domains of the CFQ-R and pediatric quality of life inventory (PedsQL 4.0) were correlated, indicating the acceptable concurrent validity (r=0.5-0.7). In addition, test-retest reliability was assessed using correlation-coefficients, which were considered significant for both the child version (r=0.88; P˂0.001) and parent version (r=0.78; P˂0.001). Moreover, the CFQ-R scales showed significant correlations with the clinical indices and the construct of disease severity in the child and parent version.
Conclusion: According to the results, the Persian version of the child and parent CFQ-R has acceptable reliability and validity indices; and may be suggested to be used in clinical trials for the clinical evaluations and follow-ups of Iranian children with CF.
Keywords
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