Prevalence of Polycystic Ovary Syndrome among Girls’ Students of Kerman University of Medical Sciences and a Meta-Analysis of the Prevalence of PCOS among Iranian Adolescent Girls

Fattah, Abolfazl; Hadavi, Farnaz; Bahrami, Fereshteh; Khoshkholgh, Roghaie; Ahmadi, Atefeh; Mahmoodabadi, Motahare; Salari Nasab, Jaleh; Bamorovat, Zahra; Basri, Seyed Abdul Rasool; Hosseinnataj, Abolfazl; Ghazanfarpour, Masumeh

doi:10.22038/ijp.2021.57752.4528

Prevalence of Polycystic Ovary Syndrome among Girls’ Students of Kerman University of Medical Sciences and a Meta-Analysis of the Prevalence of PCOS among Iranian Adolescent Girls

Document Type : original article

Authors

Abolfazl Fattah ¹

Farnaz Hadavi ²

Fereshteh Bahrami ³

Roghaie Khoshkholgh ⁴

Atefeh Ahmadi ⁵

Motahare Mahmoodabadi ⁶

Jaleh Salari nasab ⁶

Zahra Bamorovat ⁶

Seyed Abdul Rasool Basri ⁷

Abolfazl Hosseinnataj ⁸

Masumeh Ghazanfarpour ⁶

¹ Research Center for Health Sciences and Technologies, Semnan University of Medical Sciences, Semnan, Iran.

² Department of Obstetrics and Gynecology Ardabil University of Medical Sciences: Ardabil, Iran.

³ Shiraz University of Medical Science, Shiraz, Iran.

⁴ Department of Midwifery, Firoozabad Branch, Islamic Azad University, Firoozabad, Iran.

⁵ Nursing Research Center, Department of Counselling in Midwifery, Razi Faculty of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran.

⁶ Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.

⁷ BSc in Nursing, Faculty of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran.

⁸ Assistant Professor, Department of Biostatistics Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.

10.22038/ijp.2021.57752.4528

Abstract

Background: The main objective of the present study was to investigate the prevalence of the polycystic ovary syndrome (PCOS) among girls’ students of Kerman University of Medical Sciences and its relationship with anthropometric indices and the secondary purpose included a meta-analysis of the prevalence of PCOS in Iranian adolescent girls.
Materials and Methods: In the first part, the cross-sectional descriptive study was carried out on 636 students residing in dormitories of Kerman University of Medical Sciences. Cluster sampling was used and stepwise logistic regression was used to evaluate the factors affecting the prevalence of PCOS. In the second part of the study, online databases were searched in Scopus, PubMed, Web of Science, EMABSE and Persian Magiran, SID, and Iran Doc databases basis of inclusion-exclusion criteria until January 2020. STROBE checklist was used to measure for evaluating of study quality.
Results: At firs part, 636 girl's students participant in this study. A total of 73 patients (11.5%) had PCOS. There was a significant relationship only between waist circumference with the prevalence of PCOS. For every one centimeter increase in waist circumference, the odds ratio of developing PCOS increases by 7%. According to the findings of six studies in the present meta-analysis, the prevalence of PCOS is 5.2% (95% CI: 3-8%). Heterogeneity cross studies was highly significant (p <0.01; I₂=94%).
Conclusion: The prevalence of PCOS in adolescents and childbearing age group is not high in Iran. The results of the present study showed a significant relationship between waist circumferences (WC) with the prevalence of PCOS, so that for one-centimeter increase in WC, the odds ratio of developing PCOS increases by 7%.

Keywords

Girls

Prevalence

Polycystic Ovary Syndrome

Meta-analysis

Students