<?xml version="1.0" encoding="utf-8"?>
			<journal>
			<title>Journal of Pediatric Perspectives</title>
			<title_fa></title_fa>
			<short_title>JPP; J Ped Perspect</short_title>
			<subject>Medical Sciences</subject>
			<web_url>https://jpp.mums.ac.ir/</web_url>
			<journal_hbi_system_id>0</journal_hbi_system_id>
			<journal_hbi_system_user></journal_hbi_system_user>
			<journal_id_issn></journal_id_issn>
			<journal_id_issn_online>3060-7205</journal_id_issn_online>
			<journal_id_pii></journal_id_pii>
			<journal_id_doi></journal_id_doi>
			<journal_id_iranmedex></journal_id_iranmedex>
			<journal_id_magiran></journal_id_magiran>
			<journal_id_sid></journal_id_sid>
			<journal_id_nlai></journal_id_nlai>
			<journal_id_science></journal_id_science>
			<language>en</language>
			<pubdate>
				<type>jalali</type>
				<year>0</year>
				<month>0</month>
				<day>1</day>
			</pubdate>
			<pubdate>
				<type>gregorian</type>
				<year>2026</year>
				<month>2</month>
				<day>1</day>
			</pubdate>
			<volume>14</volume>
			<number>2</number>
			<publish_type>online</publish_type>
			<publish_edition>1</publish_edition>
			<article_type>fulltext</article_type>
			<articleset><article>
				<language>en</language>
				<article_id_issn></article_id_issn>
				<article_id_issn_online></article_id_issn_online>
				<article_id_pubmed></article_id_pubmed>
				<article_id_pii></article_id_pii>
				<article_id_doi></article_id_doi>
				<article_id_iranmedex></article_id_iranmedex>
				<article_id_magiran></article_id_magiran>
				<article_id_sid></article_id_sid>
				<title_fa></title_fa>
				<title>Non-Thyroidal Illness Syndrome in A Pediatric Intensive Care Unit During COVID-19 Era</title>
				<subject_fa></subject_fa>
				<subject></subject>
				<content_type_fa></content_type_fa>
				<content_type>original article</content_type>
				<abstract_fa><![CDATA[]]></abstract_fa>
				<abstract><![CDATA[Background: Non-thyroidal illness syndrome (NTIS) is defined as a condition that occurs during acute illness. In this study, we evaluated thyroid function tests in pediatric patients with coronavirus disease 2019 (COVID-19) infection who were admitted to the pediatric intensive care unit (PICU) and compared them with children admitted to the PICU due to other disordersMaterials and Methods: This was a cross-sectional study where all patients between the ages of 1 month and 16 years admitted to the COVID-19 referral Hospital PICUs were evaluated over a 6 month period. A checklist was used to gather patient information. Thyroid hormones evaluated included; measurements of free T3, T3, T4 and TSH on the first day of admission Data was analyzed using the SPSS 21 statistical package.Results: A total of 73 patients were evaluated during the 6 month study period. 40 (54.8%) of them were male and 53(45.2%) were female. The mean age of the study population was 5.9±4.3 years.13 patients were admitted due to SARS-Cov-19 infection.Thyroid function consistent with Non thyroidal illness syndrome was observed in 25(34.2%) of these patients. The level of T3 and FT3 in patients with COVID-19 were significantly lower than in patients without COVID-19 infection (P&lt;0.05). Body temperature in patients with abnormal thyroid tests was significantly higher than in patients with normal thyroid tests (P=0.040).Conclusion: We found that one-third of children admitted to the PICU had NTIS. We suggest that FT3 can be a marker of COVID-19 patient severity, as its lower levels were observed in pediatric patients admitted to the PICU.]]></abstract>
				<keyword_fa></keyword_fa>
				<keyword>Covid-19 infection, Non thyroidal illness syndrome, Pediatric</keyword>
				<start_page>19912</start_page>
				<end_page>19919</end_page>
				<web_url>https://jpp.mums.ac.ir/article_27472.html</web_url>
			<author_list><author>
				<first_name>Majid</first_name>
				<middle_name></middle_name>
				<last_name>Sezavar Dokht Faroughi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>sezavardm@mums.ac.ir</email>
				<code>120668</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Nosrat</first_name>
				<middle_name></middle_name>
				<last_name>Ghaemi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>ghaemin@mums.ac.ir</email>
				<code>120669</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Mohadeseh</first_name>
				<middle_name></middle_name>
				<last_name>Abotorabi</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>mohi.ab76@gmail.com</email>
				<code>120670</code>
				<coreauthor>No</coreauthor>
				<affiliation>Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Sepideh</first_name>
				<middle_name></middle_name>
				<last_name>Bagheri</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>bagheris@mums.ac.ir</email>
				<code>120671</code>
				<coreauthor>No</coreauthor>
				<affiliation>Department of Pediatrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author><author>
				<first_name>Nafiseh</first_name>
				<middle_name></middle_name>
				<last_name>Pourbadakhshan</last_name>
				<suffix></suffix>
				<first_name_fa></first_name_fa>
				<middle_name_fa></middle_name_fa>
				<last_name_fa></last_name_fa>
				<suffix_fa></suffix_fa>
				<email>pourbadakhshann@mums.ac.ir</email>
				<code>120672</code>
				<coreauthor>Yes</coreauthor>
				<affiliation>Clinical Research Development Unit of Akbar Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.</affiliation>
				<affiliation_fa></affiliation_fa>
				 </author></author_list>
				</article>
			</articleset>
			</journal>