Journal of Pediatric Perspectives

Background: Abnormal growth in children with autoimmune hepatitis (AIH) is anticipated, either due to hepatic affection or the growth inhibitory effects of corticosteroids. We aimed ... Read More Background: Abnormal growth in children with autoimmune hepatitis (AIH) is anticipated, either due to hepatic affection or the growth inhibitory effects of corticosteroids. We aimed to describe children's anthropometry with AIH, and study the factors affecting height.Methods: The present observational study investigates the anthropometric measures of 28 children with AIH followed at a university hospital for 9.5±3 years. We calculated the initial AIH score, the Child-Pugh score, and the pediatric end-stage liver disease score (PELD), follow-up anthropometry, and corticosteroid history. We defined abnormal growth as under nutrition (underweight, wasting, stunting), short stature, overweight, and obesity.Results: At AIH diagnosis, children had a mean age of 7.4±3.1 years, ranging from 2 to 13.8; among whom ~20% had ascites, ~79% had jaundice, and ~82% had type 1 AIH, ~70% had a definite diagnosis of AIH, ~64% were Child-Pugh Score B, ~64% showed severe fibrosis/cirrhosis, and the median PELD score was 8.1 (0.1-12.1). At follow-up, their mean age was 15.9±1.6 years, with mean corticosteroid duration of 7.1±3.1 years, and remission occurred in 50%. We observed a significant improvement in the initial rates of underweight (46.4% vs. 17.8%), mainly stunted, and increased rates of overweight/obesity (14.3% vs. 32.2%). The final rates of height affection without weight affection were comparable to the initials (28.6% vs. 32.1%). Cases with abnormally low final height had significantly more frequent Child-Pugh Score B, higher PELD score, and severe hepatic fibrosis at presentation, with no difference regarding the continuation/ total duration of steroids.Conclusion: the final height in children with AIH is significantly affected by the disease severity at presentation and not the continuation or the duration of corticosteroids use.Background: Abnormal growth in children with autoimmune hepatitis (AIH) is anticipated, either due to hepatic affection or the growth inhibitory effects of corticosteroids. We aimed to describe children's anthropometry with AIH, and study the factors affecting height.Methods: The present observational study investigates the anthropometric measures of 28 children with AIH followed at a university hospital for 9.5±3 years. We calculated the initial AIH score, the Child-Pugh score, and the pediatric end-stage liver disease score (PELD), follow-up anthropometry, and corticosteroid history. We defined abnormal growth as under nutrition (underweight, wasting, stunting), short stature, overweight, and obesity.Results: At AIH diagnosis, children had a mean age of 7.4±3.1 years, ranging from 2 to 13.8; among whom ~20% had ascites, ~79% had jaundice, and ~82% had type 1 AIH, ~70% had a definite diagnosis of AIH, ~64% were Child-Pugh Score B, ~64% showed severe fibrosis/cirrhosis, and the median PELD score was 8.1 (0.1-12.1). At follow-up, their mean age was 15.9±1.6 years, with mean corticosteroid duration of 7.1±3.1 years, and remission occurred in 50%. We observed a significant improvement in the initial rates of underweight (46.4% vs. 17.8%), mainly stunted, and increased rates of overweight/obesity (14.3% vs. 32.2%). The final rates of height affection without weight affection were comparable to the initials (28.6% vs. 32.1%). Cases with abnormally low final height had significantly more frequent Child-Pugh Score B, higher PELD score, and severe hepatic fibrosis at presentation, with no difference regarding the continuation/ total duration of steroids.Conclusion: the final height in children with AIH is significantly affected by the disease severity at presentation and not the continuation or the duration of corticosteroids use.

Growth Pattern Investigation in Cow’s Milk Allergic Proctocolitis in Those Who are Under Elimination Diet

Mohadese Khakpour; Nasrin Moazzen; Ali Khakshour; Samaneh Norouziasl; Saeedeh Talebi; Hamidreza Kianifar

Volume 8, Issue 11 , November 2020, , Pages 12455-12460

https://doi.org/10.22038/ijp.2020.47183.3829

Abstract

Background Cow’s milk allergy is one of most prevalent food allergies worldwide. Due to elimination diet it can impair growth in infants. In this study we evaluate ... Read More

Effect of Fenugreek on Breastfeeding Adequacy in Breastfeeding Mothers: A Review Study

Mahla Salarfard; Somayeh Moeindarbary; Zahra Khojastehfard; Fahime Vafisani; Zoleykha Asgarlou; Mehrdad Khodabandeh; Ali Rokni; Farzane Ashrafinia

Volume 8, Issue 8 , August 2020, , Pages 11831-11836

https://doi.org/10.22038/ijp.2020.47365.3843

Abstract

Background Effective interventions on exclusive breastfeeding that are appropriate for the existing conditions can have significant benefits on maintenance, continuity, and promotion ... Read More

Effect of Magnetic Fields during Pregnancy on Fetal Growth and Preterm Labor: A Review Article

Zahra Khojastehfard; Somayeh Ghahremani; Maryam Sabaghian; Samaneh Ghalebizadeh; Zoleykha Asgarlou; Soheil Mohammadi Yazdi; Mahla Salarfard

Volume 8, Issue 5 , May 2020, , Pages 11371-11375

https://doi.org/10.22038/ijp.2020.48094.3874

Abstract

Background Low birth weight is one of the most important health indicators in evaluating pregnancy care worldwide. We aimed to evaluate the effect of cell phones used in pregnancy on ... Read More

Growth Assessment and Vitamin D Level in Egyptian Juvenile Idiopathic Arthritis Patients

Rasha Abdel-magied; Gihan Omar; Sheren Maher

Volume 7, Issue 8 , August 2019, , Pages 9987-9995

https://doi.org/10.22038/ijp.2019.41070.3460

Abstract

Background Juvenile idiopathic arthritis (JIA) is one of the most common rheumatic diseases in childhood and is frequently associated with growth retardation. Vitamin D is critical ... Read More

The Relationship between Developmental Growth of Children and Anthropometric Indices in Urmia City, North West of Iran

Moradali Zareipour; Ali Sadaghianifar; Mousa Ghelichi Ghojogh; Hamideh Ebrahimi; Parvin Asgharzadeh; Rohollah Valizadeh; Hamidreza Farrokh-Eslamlou

Volume 5, Issue 5 , May 2017, , Pages 4975-4984

https://doi.org/10.22038/ijp.2017.22214.1857

Abstract

Background The developmental delays of children, is one of the most important sources of information to detect the developmental delays of children. The aim of this study was to investigate ... Read More

Survey on the Relationship between Sleep Habits and Children`s Growth in Ahvaz City 2015

Sara Moradnia; Mohammad Adineh; SHahla Esferanjani; SHahram Baraz

Volume 4, Issue 6 , June 2016, , Pages 1943-1951

https://doi.org/10.22038/ijp.2016.6824

Abstract

Background: Exact determination between children's sleep habits and their growth could help us to prevent this risk factor of children's growth disorders. Thus this research was performed ... Read More

Assessment the Relationship Between Parents' Literacy Level with Children Growth in Mashhad: An Analytic Descriptive Study

Masumeh Saeidi; Rahim Vakili; Bibi Leila Hoseini; Ali Khakshour; Behjat Zarif; Somayeh Nateghi

Volume 1, Issue 2 , December 2013, , Pages 39-43

https://doi.org/10.22038/ijp.2013.2258

Abstract

Introduction: Present children are the investments of community in the future. Preparing children health which leads to the stability of community health, provided to accurate implementation ... Read More

Journal of Pediatric Perspectives

Articles in Press

Current Issue

Volume 12 (2024)

Volume 11 (2023)

Volume 10 (2022)

Volume 9 (2021)

Volume 8 (2020)

Volume 7 (2019)

Volume 6 (2018)

Volume 5 (2017)

Volume 4 (2016)

Volume 3 (2015)

Volume 2 (2014)

Volume 1 (2013)

Keywords = Growth

Growth and Final Height in Children with Autoimmune Hepatitis; A long term observation

Abstract

Growth Pattern Investigation in Cow’s Milk Allergic Proctocolitis in Those Who are Under Elimination Diet

Abstract

Effect of Fenugreek on Breastfeeding Adequacy in Breastfeeding Mothers: A Review Study

Abstract

Effect of Magnetic Fields during Pregnancy on Fetal Growth and Preterm Labor: A Review Article

Abstract

Growth Assessment and Vitamin D Level in Egyptian Juvenile Idiopathic Arthritis Patients

Abstract

The Relationship between Developmental Growth of Children and Anthropometric Indices in Urmia City, North West of Iran

Abstract

Survey on the Relationship between Sleep Habits and Children`s Growth in Ahvaz City 2015

Abstract

Assessment the Relationship Between Parents' Literacy Level with Children Growth in Mashhad: An Analytic Descriptive Study

Abstract