Journal of Pediatric Perspectives

Comparing the Growth and Development of Six Months Infants between the Mothers With/Without Covid-19 during Their Pregnancy

Kokab Namakin; Zohre Saadatinasab; Hamid Salehiniya; Amirhosein Zardast

Volume 11, Issue 4 , April 2023, , Pages 17558-17571

https://doi.org/10.22038/ijp.2023.69768.5148

Abstract

Background: Viral infection during pregnancy induces pro-inflammatory cytokines and increases the level of IL-6, which as a measure of the inflammation of the mother's immune system ... Read More Background: Viral infection during pregnancy induces pro-inflammatory cytokines and increases the level of IL-6, which as a measure of the inflammation of the mother's immune system is effective on the development of the brain of the fetus and increases the rate of mental disorders of the fetus. The possible effect of the mother's COVID-19 on children, if any, is still unknown. Therefore, this study was conducted with the aim of investigating and comparing the consequences of neurodevelopment and growth at the age of 6 months in infants among mothers with/without exposure to COVID-19 during pregnancy in Birjand, 2021.Methods: A total of 161 pregnant women with PCR-positive coronavirus and 181 pregnant women without infection were selected by simple random sampling. Demographic characteristics including age, occupation, education, gender, nationality, sex of babies, along with data related to the neurodevelopmental status of infants by the use of ASQ questionnaire were extracted and entered into SPSS 16 software. For descriptive statistics, Mean, standard deviation, and frequency distribution tables were used, and inferential analyses were conducted by the use of Chi-square, t-test, and analysis of variance at a significance level of less than 0.05. The disturbance was equal / lower than 1 SD in each of ASQ-3 score domains.Results: In this cohort study, demographic characteristics in the exposed and unexposed groups were not significantly different. There was no statistically significant difference between the average score of the ASQ_3 questionnaires as well as the average score in the areas of communication, gross motor, fine motor, problem-solving, and social personality among infants born from mothers with and without COVID-19. Also, there was no significant difference in the incidence of disorders in different fields of neurodevelopment, except for the field of establishing communication between the two groups of exposed and unexposed. On the other hand, cesarean delivery was significantly higher in pregnant mothers with COVID-19 during pregnancy. However, there was no significant relationship between the incidence of COVID-19 and the rate of premature delivery, and low birth weight neonates. In addition, the severity and time of the corona infection during pregnancy did not have any significant effect on the neurodevelopment of infants with intrauterine exposure to COVID-19.Conclusion: According to the results of the study, infection with COVID-19 does not increase the incidence of developmental disorders in 6-month-old infants. Furthermore, it does not increase low

A Comparison of Serum Magnesium and Blood Sugar Levels between Obese and Normal-Weight Adolescents

mahmoud zardast; Amirhosein Zardast; kookab Namakin.; Gholam Reza Sharifzadeh; Maryam Khodaparast

Volume 10, Issue 12 , December 2022, , Pages 17077-17084

https://doi.org/10.22038/ijp.2022.67776.5058

Abstract

Background: In recent years, there has been a sharp rise in the prevalence of obesity across all age groups, which poses a serious threat to public health. Numerous micronutrients, ... Read More Background: In recent years, there has been a sharp rise in the prevalence of obesity across all age groups, which poses a serious threat to public health. Numerous micronutrients, including magnesium, are deficient in obese people. Magnesium is a vital cofactor for hundreds of enzyme systems and is involved in the metabolism of sugars, proteins, and lipids. Obesity is one of the most significant risk factors associated with the development of glucose intolerance, cardiovascular disease, high blood pressure, and hyperlipidemia. Given the recent rise in obesity at young ages, this study aimed at comparing serum magnesium and blood sugar levels between obese and normal-weight adolescents. Methods: In this case-control study, fifty-seven 12-18-year-old obese and overweight adolescents (BMI above 85% as the case group) and normal-weight adolescents (BMI between 65% and 85% as the control group) were selected randomly from high schools across Birjand. Upon recruitment and assignment of participants, blood samples were collected and serum magnesium and glucose levels were measured. SPSS 15 software was utilized to analyze the collected data. Results: Age and gender distributions were similar between the case and control groups (P> 0.05). The mean serum magnesium concentration was significantly lower in the case group than in the control group (P <0.05). The mean blood sugar level in the case group was significantly higher than that in the control group (P <0.05). There was no correlation between blood glucose and magnesium in the two groups (P> 0.05). Conclusion: The mean serum magnesium concentration of overweight and obese adolescents is lower than that of normal-weight children. Therefore, serum Mg may serve as an early biomarker for predicting obesity-related diseases. Further research is required to evaluate the precise role of magnesium in obesity prevention and to establish the causal relationship between obesity and magnesium deficiency.

Journal of Pediatric Perspectives

Articles in Press

Current Issue

Volume 12 (2024)

Volume 11 (2023)

Volume 10 (2022)

Volume 9 (2021)

Volume 8 (2020)

Volume 7 (2019)

Volume 6 (2018)

Volume 5 (2017)

Volume 4 (2016)

Volume 3 (2015)

Volume 2 (2014)

Volume 1 (2013)

Author = Kokab Namakin

Comparing the Growth and Development of Six Months Infants between the Mothers With/Without Covid-19 during Their Pregnancy

Abstract

A Comparison of Serum Magnesium and Blood Sugar Levels between Obese and Normal-Weight Adolescents

Abstract